 IVF is a time-tested procedure to
increase the chance of pregnancy. This is
a sequential process. Requiring the
harvest of oocytes from the woman's
ovary, receiving ovarian stimulation,
achieved through use of ovulation
induction medication. Success rates 20-
45% |
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| IVF-ET (IN VITRO FERTILIZATION AND EMBRYO TRANSFER) |
IVF-ET was initially considered a treatment of choice for tubal factor infertility. Thus cases of tubal disease, occlusion, adhesions or surgery were considered as other treatments could not offer comparable success. Subsequently 1VF indications expanded to include PCOS wherein better follicular growth and fertilization rates were obtained. Today the indications cover unexplained infertility, advancing maternal age, repeated trials of conservative treatments, ovarian failure, and antispcrm antibodies. IVF offers a possibility of diagnosis of gamete dysfunction. With the advent of ICSI, indications have expanded to encompass almost all cases of male infertility. |
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| EVALUATION FOR IVF—PREREQUISITES FOR RECRUITMENT |
| Patient Selection |
There has been a marked increase in patient population in all infertility clinics the world over, but all infertility clinics may not be sufficiently equipped with the latest technology and expertize essential to offer the best possible help. Hence there is a need for patient selection, in order to categorize them in specific groups and then refer them to different levels of infertility care units for step-wise investigation and treatment. |
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| PATIENT SELECTION FOR TREATMENT IN DIFFERENT INFERTILITY CARE UNITS |
In general, infertile couples can be categorized broadly into three groups:
- Those with single defect in one of the partners.
- Those with multiple defects in one or both the partners.
- No apparent defect in either partner (unexplained infertility).
- Women who have undergone premature or timely menopause
- Women in the perimenopausal age group who do not show proper recruitment of follicles and who have other existing causes of infertility
- Women with genetic disorders
- Those who have undergone radiation therapy
- Those with ovaries that are not accessible by ultrasound due to severe adhesions.
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